SQL Server Table with huge data & Columns and not all the columns are unused.

Hi,

We have a table which is of a huge size 300+GB and it is growing at a 25Gb per month. We have identified that there are columns which are not being used.  Is it possible to do below option

Do a partition based on column and then implement compression based on the unused columns.

Let me know if it is doable and also if possible any examples

thanks

Vamc435

vamshi