Transaction replication getting same error continuously

Hello Team,

We are configured transaction replication from sql server 2005 to sql server 2008R2,

My distribution database is located in publication server i.e sql server 2005.

Replication working fine there is no issue.

But while we are checking sql server error log and windows event viewer it’s showing below error message continuously.

Error Message :

Replication-Replication Distribution Subsystem: agent domain\abc- replication_Repl-domain\abc-3 failed. The distribution agent failed to create temporary files in 'C:\Program Files\Microsoft SQL Server\100\COM' directory. System returned errorcode 5

Note: my distribution located in sql server 2005 but above error message showing compatibility level 100.

Please provide me your values inputs and how fix this issue ASAP.

Thanks